Topamax (topiramate) Full Profile. page 2

Other medications:
Be sure to tell your doctor if you are taking any other prescription or over-the-counter medications, especially:

• Acetazolamide (Diamox)
• Carbamazepine (Tegretol)
• Dichlorphenamide (Daranide)
• Oral contraceptives
• Phenytoin (Dilantin)
• Valproic acid (Depakene, Depakote)

Potential side effects:

• Check with your doctor as soon as possible if any of the following side effects occurr:
  • More common:
    • any vision problems, especially blurred vision, double vision, eye pain, rapidly decreasing vision, eye redness, increased eye pressure
    • burning, prickling, or tingling sensations
    • clumsiness or unsteadiness
    • confusion
    • continuous, uncontrolled back-and-forth or rolling eye movements
    • dizziness
    • drowsiness
    • generalized slowing of mental and physical activity
    • memory problems
    • menstrual changes or pain
    • nervousness
    • speech or language problems
    • trouble in concentrating or paying attention
    • unusual tiredness or weakness
  • Less common:
    • abdominal pain
    • fever, chills, or sore throat
    • lessening of sensations or perception
    • loss of appetite
    • mood or mental changes including aggression, agitation, apathy, irritability, and mental depression
    • red, irritated, or bleeding gums
    • weight loss
  • Rare:
    • blood in urine
    • decrease in sexual performance or desire
    • difficult or painful urination
    • eye pain
    • frequent urination
    • hearing loss
    • itching
    • loss of bladder control
    • lower back or side pain
    • nosebleeds; pale skin
    • red or irritated eyes
    • ringing or buzzing in ears
    • skin rash
    • swelling
    • troubled breathing
• These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
  • More common:
    • breast pain in women
    • nausea
    • tremors
  • Less common:
    • back pain
    • chest pain
    • hair loss or change in hair texture
    • constipation
    • heartburn
    • hot flushes
    • increased sweating
    • leg pain

Brand Names:

• U.S.: Topamax^®
• Canada: Topamax^®
• U.K.: Topamax^®
• Australia: Topamax^®

More Information:

• International Symposium, Topamax Study
• Topamax for Prevention: Proper Dosage and Taper
  Topamax (topiramate), a medication originally developed for seizure control, has been prescribed for several years now for prevention of cluster headaches and Migraine attacks. Here's important information about how to best use this medication.
• Topamax: Take With Caution
  Manufacturer Ortho-McNeil has issued a warning letter to health care professionals regarding newly discovered potential side effects of Topamax, myopia and glaucoma.
• FDA warning regarding visual side effects[/link]
• Topamax: New Safety Alert
  The FDA and Ortho-McNeil, the manufacturer of Topamax (topiramate) have issued a new safety alert. The warning concerns reports of oligohidrosis (decreased sweating) and hyperthermia. These side effects may have potential serious consequences, which may be preventable by promptly recognizing the symptoms and seeking immediate treatment. Patients, especially pediatric patients, treated with TOPAMAX should be monitored closely for evidence of decreased sweating and increased body temperature, especially in hot weather.
• FDA-approved prescribing info (Requires free Adobe Acrobat Reader)

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