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Botox: Headache and Migraine Drug Profiles.
Botox (botulinum toxin type A)

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Type of medication: Rx, doctor-administered, preventive
Botulinum toxin type A is a toxin produced by the bacteria that causes botulism. Botulinum toxin type A affects the nerves. When injected into a muscle, it produces a reduction in the activity of the muscle. Botulinum toxin type A is used to reduce abnormal head position and neck pain in patients with cervical dystonia (spasms of the neck muscles). Botulinum toxin type A is also used in the treatment of strabismus (a condition in which the eyes do not point in the same direction) and spasms of the eyelids or uncontrollable blinking (blepharospasm). Botulinum toxin type A is used cosmetically for the temporary improvement in the appearance of some facial wrinkles. It is also being used as a Migraine preventive.

Precautions:

  • Do not use botulinum toxin type A without first talking to your doctor if you have
    • a neuromuscular disorder such as amyotrophic lateral sclerosis (ALS), myasthenia gravis, Lambert-Eaton syndrome, and others
    • an infection at the intended site of injection

Pregnancy and Breastfeeding:

  • FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not use botulinum toxin type A without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether botulinum toxin type A passes into breast milk. Do not use botulinum toxin type A without first talking to your doctor if you are breast-feeding a baby.

Other medical conditions:
Do not use botulinum toxin type A without first talking to your doctor if you have

  • a neuromuscular disorder such as amyotrophic lateral sclerosis (ALS), myasthenia gravis, Lambert-Eaton syndrome, and others
  • an infection at the intended site of injection.

Other medications:
Botulinum toxin type A should not be used with other forms of botulinum toxin or other medications that affect the nerves or muscles, except under the direction of a doctor.

Potential side effects:

  • Seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
    • difficulty breathing, talking, or swallowing
    • unusual or excessive muscle weakness
    • chest pain or irregular heartbeats
    • eye infection, ulceration, double vision, or other eye problems..
  • Other less serious side effects may be more likely to occur. Talk to your doctor if you experience:
    • headache
    • dizziness or drowsiness
    • soreness at the injection site
    • nausea
    • eye tearing or irritation
    • eyelid swelling

Brand Names:

  • U.S.: Botox

More Information:

  • Treating Pain Disorders With Intradermal Botox
    We've all heard a lot about Botox, botulinum Toxin Type A (BoNTA). It seems as if it's being used for something different every day. There are both cosmetic and medical applications for it. In the right hands, Botox is very helpful. Research into the most effective ways to use Botox for headache and Migraine treatment continues and is promising. Here, we'll take a look at research performed by John Claude Krusz, Ph.D., M.D., and William R. Knoderer, M.D., D.D.S., in Dallas.
  • Botox for Head Pain, Largest Study Yet
    Botox! We keep hearing about it in the news and discussing it in our forums. Now, the results of the largest study to date regarding Botox and a headache and Migraine preventive are out: Botulinum toxin type A, brand name Botox®, is an effective preventative therapy for headache and Migraine pain in chronic sufferers, according to the largest study performed to date, presented at the 45th Annual Scientific Meeting of the American Headache Society (AHS).
  • Poison Your Migraine?
    When many people hear the words Botulinum Toxin, the first thing they think of is botulism, an often fatal form of food poisoning. Botulism is caused by some strains of Clostridium botulinum, bacteria that is generally found in badly canned foods. In recent years, however, scientists have discovered that a certain strain of Clostridium botulinum can safely be used as a drug to prevent migraine attacks.

Material on this page is for informational purposes only, and should not be construed as medical advice. Always consult your physician or pharmacist regarding medications.

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