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Husband's migraines increasing... triptan rebound... preventives?

From John Claude Krusz, MD, PhD, and Teri Robert, for About.com

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Question: Husband's migraines increasing... triptan rebound... preventives?

Answer:

Full Question:

My husband is 35 and has been having migraines for the past 15 years. 10 years ago, he only had a migraine twice a year, about two years ago they increased to about twice a week (while completing his masters degree). Triptans control these effectively, but he gets a rebound headache unless he cycles between triptans. He went on Depakote for 5 months, but the side effects made life difficult and he was still having 3 migraines a week. He tapered off the Depakote (following Drs advice). Once completely off the Depakote he experienced the same level of migraines but additionally had constant nausea, other headaches, and disassociation (like a constant migraine with out the specifically migraine headache). An MRI showed unusually large ventricles (for his age) and some random white matter. He tried propranolol for 6 weeks with no effect. He is now on his 6th week of Topamax with no effect on the migraines but some reduction of daily headaches. Wendy.
 

Answer:

Dear Wendy;

Topamax might be good or not--the dose is? The time of treatment is still short. I'd have your husband seek out the services of a headache expert. He will likely have some headache into the future, based on his history. There's a link below to our directory of recommended specialists.

Good luck,
Teri Robert and John Claude Krusz

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Published March 6, 2006

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