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Type of medication: Rx, abortive, triptan, antimigraine agent
How supplied:
2.55 mg and 5 mg tablets, nasal spray, 2.5 mg orally dissolving tablets (U.S. only).
Precautions:
Zolmitriptan is generally not prescribed under these conditions:
- presence or risk factors for coronary
artery disease
- angina, fast or irregular heartbeat
- history of heart attack
- uncontrolled hypertension
- basilar or hemiplegic Migraines
- history of stroke
- Phenylketonuria (PKU)—The oral
disintegrating tablets may contain aspartame, which can make your
condition worse.
- allergy to or strong sensitivity to
aspartame (orally dissolving tablets only)
- Do NOT take Imitrex
within 24 hours of taking any other triptan unless specifically told to
do so by your doctor.
- Do NOT take Imitrex
within 24 hours of taking any ergotamine medication such as DHE or
Migranal.
Pregnancy and
Breastfeeding:
- FDA pregnancy category C. This means
that it is not known whether this drug will harm an unborn baby. Do not
take this medication without first talking to your doctor if you are
pregnant or could become pregnant during treatment.
- It is not known whether this
medication passes into breast milk. Do not take without talking to your
doctor if you are breast-feeding a baby.
Other medical
conditions:
The presence of other medical problems may
affect the use of zolmitriptan. Make sure you tell your doctor if you have any
other medical problems, especially those listed below. Heart or blood vessel
disease and high blood pressure sometimes do not cause any symptoms, so
some people do not know that they have these problems. Before deciding
whether you should use zolmitriptan, your doctor may need to do some tests
to make sure that you do not have any of these conditions.
- angina, heart or blood vessel
disease
- fast or irregular heart beat
- uncontrolled high blood pressure
- kidney disease
- liver disease
- stroke (history of)--The chance of
side effects may be increased.
- Phenylketonuria (PKU)—The oral
disintegrating tablets may contain aspartame, which can make your
condition worse.
- seizures or Epilepsy
- basilar or hemiplegic Migraine
Other
medications:
Be sure to tell your doctor if you are taking any other prescription or
over-the-counter medications, especially other prescription medicine for
Migraine or depression.
- Do not take zolmitriptan if you have
taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan),
tranylcypromine (Parnate), or phenelzine (Nardil) within the last 14
days. The combination could cause seizures, nausea, vomiting,
sweating, flushing, and dizziness.
- Do not take zolmitriptan if you have
taken any of the following medicines within the previous 24 hours:
- ergot-based medications such as
methysergide (Sansert), ergotamine (Ergostat), dihydroergotamine (D.H.E.,
Migranal Nasal Spray), and ergotamine combination products (Cafergot,
Ercaf, Wigraine, Cafatine, Cafatine-PB, Cafetrate).
- another triptan such as zolmitriptan
(Maxalt, Maxalt-MLT), naratriptan (Amerge), zolmitriptan (Zomig),
almotriptan (Axert), frovatriptan (Frova), or eletriptan (Relpax)
- Before taking zolmitriptan, tell your
doctor if you are taking
- a selective serotonin reuptake
inhibitor (SSRI) such as fluoxetine (Prozac), fluvoxamine (Luvox),
paroxetine (Paxil), sertraline (Zoloft), or citalopram (Celexa); or
- propranolol (Inderal)
Potential side
effects:
- Stop using zolmitriptan and contact
your doctor immediately if any of the following side effects occur:
- severe chest pain
- heaviness, tightness, or pressure in
chest and/or neck
- sensation of burning, warmth, heat,
numbness, tightness, or tingling
- changes in facial skin color
- cough or hoarseness
- difficulty in swallowing
- increased or irregular heartbeat
- fever or chills
- rash, hives, itching, or bumps on skin
- shortness of breath
- lower back, side, or abdominal pain
- painful or difficult urination
- puffiness or swelling of the eyelids
or around the eyes, face, or lips
- shortness of breath, troubled
breathing, tightness in chest, and/or wheezing
- skin rash, hives, and/or itching
- Some of the following effects, such as
nausea, vomiting, drowsiness, dizziness, and general feeling of illness
or tiredness, often occur during or after a migraine, even when
zolmitriptan has not been used. However, check with your doctor if any of
the following side effects continue or are bothersome:
- dizziness
- nausea
- sleepiness
- unusual tiredness or muscle weakness
- agitation, anxiety, or depression
- discomfort in jaw, mouth, or throat
- difficulty in swallowing
- dry mouth
- fainting
- heartburn
- itching of the skin
- large nonelevated blue or purplish
patches in the skin
- muscle aches
- sudden large increase in frequency and
quantity of urine
- sweating
- swelling of face, fingers, feet and/or
lower legs
Brand Names:
- U.S.: Zomig, Zomig-ZMT (orally
dissolving tablets)
- Canada: Zomig
- U.K.: Zomig
- Australia: Not available
More Information:
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