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Cafergot
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- Rx, abortive, ergot derivative
- generally effective, but many potential side effects including
nausea, dizziness, anxiety
- available in tablets, and suppositories
- causes severe rebound headaches when taken
often
- contraindicated for patients with hypertension or cardiac risk
factors
- Do not take caffeine and ergotamine if
you are pregnant or if you could become pregnant during treatment.
Caffeine and ergotamine is in the FDA pregnancy category X. This means
that caffeine and ergotamine can cause harm to an unborn baby. Caffeine
and ergotamine can induce uterine contractions, which can result in
abortion, and it can restrict blood flow to the fetus
- more
info
- FDA
approved prescribing information for suppositories
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Cafergot PB Suppositories
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Rx, abortive, Ergotamine tartrate, caffeine, belladonna, and
Phenobarbital
less nausea than Cafergot
sedative effect due to the Phenobarbital
see Cafergot
more information: FDA
info
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Dihydroergotamine (DHE)
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- Rx, abortive, ergot derivative
- fewer side effects than other ergots.
Nausea is major side effect, so often given with Phenergan or other
antiemetics.
- ineffective when taken orally. Available
for injection or as Migranal nasal spray
- does not cause rebound as severely as other ergots,
but still has high rebound potential
- contraindications: pregnancy, vascular
disease, poorly controlled blood pressure, angina, risk factors for
coronary artery disease
- Do not take dihydroergotamine if
your are pregnant. Dihydroergotamine can induce uterine contractions,
and it can restrict blood flow to the fetus.
- Dihydroergotamine passes into breast
milk and can cause vomiting and diarrhea in a nursing infant. Do not
take dihydroergotamine if you are breast-feeding a baby.
- Potential side effects:
- Contact your doctor immediately
if you experience severe anxiety or confusion; chest pain;
elevated blood pressure; pain in your arms, legs, lower back;
convulsions; severe vomiting or stomach pain; changes in vision;
severe weakness, shortness of breath, swelling of face, feet,
lower legs, or fingers; changes in heart rhythm.
- These side effects usually
subside but contact your doctor if they continue or are
bothersome:diarrhea, nausea, or vomiting; dizziness or drowsiness;
nervousness or restlessness; dryness of mouth.
- more
info
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Ergomar Tablets
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- Rx, abortive, ergot derivative
- generally effective, but many potential side effects including
nausea, dizziness, anxiety
- available in tablets, injections, and suppositories
- causes severe rebound headaches when taken
often
- contraindicated for patients with hypertension or cardiac risk
factors
- Do not take ergotamine if you are
pregnant or if you are planning a pregnancy. Ergotamine is in the FDA
pregnancy category X. This means that ergotamine will cause birth
defects in an unborn baby. Ergotamine can induce uterine contractions,
which can result in abortion, and it can restrict blood flow to the
fetus.
- Ergotamine passes into breast milk and
can cause vomiting and diarrhea in a nursing infant. Do not take
ergotamine if you are breast-feeding a baby.
- more
info
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Migranal Nasal Spray (Dihydroergotamine
- DHE)
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- Rx, abortive, migraine-specific
serotonin
agonist
- very safe, few side effects, in use
since 1945
- sometimes safe in cases where triptans
are not recommended, but not as effective as triptans
- Do not take dihydroergotamine if
your are pregnant. Dihydroergotamine can induce uterine contractions,
and it can restrict blood flow to the fetus.
- Dihydroergotamine passes into
breast milk and can cause vomiting and diarrhea in a nursing infant. Do
not take dihydroergotamine if you are breast-feeding a baby.
- may be
ideal for migraine patients who require multiple doses to gain relief.
- tell your doctor if you are taking any
other medications, especially: Imitrex, Zomig, Maxalt, Amerge, Cocaine,
Epinephrine by injection [e.g., Epi-Pen], other ergot medicines (ergoloid mesylates [e.g.,
Hydergine], ergonovine
[e.g., Ergotrate], methylergonovine [e.g., Methergine], methysergide [e.g.,
Sansert] or
- tell your doctor if you have other medical
conditions, especially: heart or blood vessel disease, hypertension (high blood pressure),
kidney disease, liver disease, or any infection
- Potential side effects:
- Contact your doctor as soon as possible if
you experience any of the following: chest pain; cough, fever, sneezing, or sore throat; feeling of
heaviness in chest; irregular heartbeat; itching of the skin; numbness and
tingling of face, fingers, or toes; pain in arms, legs, or lower back;
pain in back, chest or left arm; pale bluish-colored or cold hands or
feet; shortness of breath or troubled breathing; weak or absent pulses in
legs
- The following side effects
generally do not need medical attention, but check with your doctor if any of them
continue or are bothersome: Burning or tingling sensation, dryness, soreness, or pain in the nose;
change in sense of taste; diarrhea; dizziness; dry mouth; fatigue; headache;
increased sweating; nausea and or vomiting; muscle stiffness; runny and or
stuffy nose; sudden sweating and feelings of warmth; sensation of burning,
warmth, or heat; sore throat; sleepiness; unexplained nose bleeds; unusual
tiredness or weakness, anxiety; blurred vision; cold clammy skin; confusion; congestion in
chest; cough; decreased appetite; depression; difficulty swallowing;
dizziness or lightheadedness when getting up from a lying or sitting
position; ear pain; eye pain; fever; heartburn; increased watering of eyes;
increased watering of the mouth; increased yawning; muscle weakness;
nervousness; pinpoint red spots on skin; pounding heartbeat; red or
irritated eyes; ringing or buzzing in ears; skin rash; stomach pain; sudden
fainting; swelling of face, fingers, feet, or lower legs; trembling or
shaking of hands or feet; trouble in sleeping; unusual feeling of well being
- more
info
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