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Headache & Migraine Medications
(listed alphabetically)

V-Z

Is there a headache/Migraine medication missing from our profiles? If so, email headaches.guide@about.com.

           


   


Vicodin  (acetaminophen/hydrocodone)

Vioxx (Rofecoxib)
  • Rx, COX-2 inhibitor, NSAID, Migraine preventive
  • officially indicated for acute pain, but shown effective as headache abortive
  • in clinical trials for use as a migraine preventive
  • FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Rofecoxib should not be taken late in pregnancy (the third trimester) because it may affect the formation of the baby's heart. Do not take rofecoxib without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether rofecoxib passes into breast milk. Do not take rofecoxib without first talking to your doctor if you are breast-feeding.
  • Be sure to tell your doctor if you smoke; drink alcohol; have ever had an ulcer or bleeding in your stomach; have liver or kidney disease; have asthma; have congestive heart failure; have fluid retention; have heart disease; have high blood pressure; have a bleeding disorder or are taking an anticoagulant such as warfarin (Coumadin); or are taking a steroid medicine.
  • Tell your doctor about all medications you may take, especially aspirin or an aspirin-like medication; an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen; a diuretic; an  ACE inhibitor; a steroid medicine; an anticoagulant ; methotrexate (Rheumatrex, Folex); lithium (Eskalith, Lithobid, others); or rifampin (Rimactane, Rifadin, Rifater).
  • Possible side effects:
    • Discontinue Vioxx and contact your doctor immediately if you experience abdominal pain, tenderness, or discomfort; bloody, black, or tarry stools; nausea or heartburn; blood in your vomit; unexplained weight gain; swelling or water retention; unusual fatigue or lethargy; a skin rash or itching; yellowing of your skin or eyes; "flu-like" symptoms; or unusual bruising or bleeding.
    • Continue taking Vioxx, but contact your doctor, if you experience: dizziness; mild fatigue or weakness; or diarrhea.
  • more info: FDA info
  • FDA approved prescribing inforamtion

Zanaflex (tizanidine) 
  • Rx, muscle relaxant
  • FDA pregnancy C. This means that it is not known whether tizanidine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
  • It is not known whether tizanidine passes into breast milk. Do not take tizanidine without first talking to your doctor if you are breast-feeding a baby.
  • before taking Zaneflex be sure to tell your doctor if you have: liver disease, kidney disease, low blood pressure or are on medication to treat high blood pressure; or are taking birth control pills.
  • Potential side effects:
    • Discontinue use and contact your doctor immediately if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); hallucinations or abnormal behavior; or liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).
    • Continue use and talk to your doctor if you experience drowsiness or dizziness; weakness; dry mouth; increased muscle tone or spasms; or sweating.

Zofran (Ondansentron) 
  • Rx, antiemetic
  • relieves nausea, and vomiting
  • tablets or tablets that dissolve on the tongue
  • fewer side effects than most antiemetics
  • not sedating
  • FDA pregnancy category B. This means that it is not likely to harm an unborn baby. Do not take ondansetron without first talking to your doctor if you are pregnant or if you are planning a pregnancy.
  • It is also not known whether ondansetron passes into breast milk. Do not take ondansetron without first talking to your doctor if you are breast-feeding a baby.
  • Be sure to tell your doctor if you have liver disease.
  • Potential side effects:
    • Discontinue use and contact your doctor immediately if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); irregular heartbeats; or muscle cramps or uncontrollable movements.
    • Continue use and talk to your doctor is you experience headache; fatigue, drowsiness, or dizziness; anxiety or agitation; or diarrhea or constipation.

Zomig (Zolmitriptan) 
  • Rx, abortive, triptan
  • forms available: regular tablets and Zomig-ZMT, orally dissolvable tablets
  • FDA pregnancy category C. This means that it is not known whether zolmitriptan will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether zolmitriptan passes into human breast milk. Do not take zolmitriptan without first talking to your doctor if you are breast-feeding a baby.
  • be sure to tell your doctor if you have:
    • taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days;
    • taken an ergot-based medication within the last 24 hours--ergot-based medicines include methysergide (Sansert), ergotamine (Ergostat, Medihaler Ergotamine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray), and ergotamine combination products (Cafergot, Ercaf, Wigraine, Cafatine, Cafatine-PB, Cafetrate);
    • taken almotriptan (Axert), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or sumatriptan (Imitrex) within the last 24 hours;
    • have basilar or hemiplegic migraine headaches;
    • have had a heart attack, have angina (chest pain), have irregular heartbeats, or have another type of heart disease; or
    • or are experiencing a headache that is not like other migraines you have had.
    • risk factors for heart disease such as high blood pressure, a family history of heart disease, high cholesterol (a type of fat), are overweight, diabetes, smoke cigarettes, are postmenopausal, are a male over 40 years of age;
    • liver disease;
    • kidney disease; or
    • seizures or epilepsy.
  • Potential side effects:
    • Discontinue use and contact your doctor immediately if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or severe or prolonged chest pain or an irregular heartbeat.
    • Continue use and talk to your doctor if you experience dry mouth; nausea; muscle tiredness or weakness; drowsiness or dizziness; or tingling, tightness, warmth, or heaviness in a body part.
  • more info: more info 
  • also see: Zomig: A New Dissolving Tablet & More To Come!

Zonegran (zonisamide) 
  • Rx, anticonvulsant, Migraine preventive
  • FDA pregnancy category C. This means that it is not known whether zonisamide will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether zonisamide passes into breast milk. Do not take zonisamide without first talking to your doctor if you are breast-feeding a baby.
  • before taking Zonegran be sure to tell your doctor if you have:
    • ever had an allergic reaction to a sulfa drug such as sulfamethoxazole (Gantanol, others); sulfisoxazole (Gantrisin, others); or sulfamethoxazole-trimethoprim (Bactrim, Bactrim DS, Septra, Septra DS, Cotrim, others). You may also have an allergic reaction to zonisamide.
    • liver or kidney disease.
  • Potential side effects:
    • Discontinue use and contact your doctor immediately if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
      a rash; worsening seizures; fever, sore throat, sores in your mouth, or bruising easily (may be signs of a blood problem); sudden back pain, stomach or abdominal pain, pain when urinating, bloody or dark urine (may be signs of a kidney stone); decreased sweating or a rise in body temperature; depression; severe drowsiness, difficulty concentrating, or coordination problems; unusual thoughts; or speech or language problems including difficulty finding words.
    • Continue use and talk to your doctor if you experience dizziness; mild drowsiness; loss of appetite; headache; nausea; or agitation or irritability.
  • more info: more info 
  • FDA approved prescribing information

Material on this page is for informational purposes only,
and should not be construed as medical advice.
Always consult your physician or pharmacist regarding medications.

 


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